Schweiz Med Wochenschr; 100(7):301-3. Applies only to oral form of both agents. Do not dilute to concentrations below 1 mg/mL [see How Supplied/Storage and Handling [16.2].) Monitor Closely (1)esomeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Ferric gluconate: 12.5 mg/mL Schrier SL, Mentzer WC, Landaw SA. Minor/Significance Unknown. Use Caution/Monitor. By taking into account the case of a patient weighing 78 kg (172 lbs) and having a hemoglobin level of 11 g/dL (110 g/L or 6.83 mmol/L). Avoid or Use Alternate Drug. 2.1 . Applies only to oral form of both agents. Copyright 2014 - 2023 The Calculator .CO |All Rights Reserved|Terms and Conditions of Use, Intravenous iron-dextran: therapeutic and experimental possibilities, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Treatment of iron deficiency anemia associated with gastrointestinal tract diseases, Diagnosis and management of iron deficiency anaemia: a clinical update. Applies only to oral form of both agents. The dosage of Venofer is expressed in mg of elemental iron. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. Applies only to oral form of both agents. The therapeutic management of IDA focuses on the replenishment of the iron stores through methods that have been mentioned above. Administer Venofer early during the dialysis session (generally within the first hour). If you log out, you will be required to enter your username and password the next time you visit. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. Applies only to oral form of both agents. Corrected Sodium and Effective Osmolality. Assessing new treatment options. This may be helped by giving the medication more slowly or at a lower dose. Iron deficit - equation derivation: Assumptions: -Blood volume = 65 mL/kg -Hemoglobin conc target =14.0 g/dL -Deficits in body stores are ignored. Avoid or Use Alternate Drug. Read our. Diluted with 0.9% Sodium Chloride Injection at concentrations of 1 to 2 mg/mL, 2 doses of 300 mg/250 mL over 1.5 hrsplus1 dose of 400 mg/250 mL over 2.5 hrs. Applies only to oral form of both agents. 1970;100(7):301303. The recommended Feraheme dose may be readministered to patients with persistent or recurrent iron deficiency anemia. Parenteral iron supplementation. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. iron sucrose increases levels of calcium carbonate by enhancing GI absorption. Applies only to oral form of both agents. iron sucrose decreases levels of ibandronate by inhibition of GI absorption. Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)- . cimetidine will decrease the level or effect of iron sucrose by increasing gastric pH. Schweiz Med Wochenschr. Give each dose as 750 mg for a total cumulative dose not to exceed 1500 mg of iron per course. Applies only to oral form of both agents. Applies only to oral form of both agents. Where C= concentration of The cost of Venofer is $145 for a dose of 300 mg and Monoferric is $274 for a dose of 500mg. LBW = Lean body weight in kg. Administer Venofer 200 mg undiluted as a slow intravenous injection over 2 to 5 minutes or as an infusion of 200 mg in a maximum of 100 mL of 0.9% NaCl over a period of 15 minutes. Patients with a history of drug allergy or multiple drug allergies may be at increased risk of anaphylactic-type reactions to INFeD. Follow your doctor's directions carefully.Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft).A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Minor/Significance Unknown. INFeD is given undiluted at a slow gradual rate not to exceed 50 mg (1 mL) per minute. Monitor Closely (1)deferoxamine decreases levels of iron sucrose by inhibition of GI absorption. Most Venofer has not been studied in patients younger than 2 years old. Hollands J, Foote E, Rodriguez A. Mean Corpuscular Hemoglobin Concentration (MCHC) Calculator, Red Blood Cell (RBC) Indices Calculator, Iron Deficiency In Pregnancy Calculator. Otherwise, call a poison control center right away. Serious - Use Alternative (1)iron sucrose decreases levels of tetracycline by inhibition of GI absorption. Use Caution/Monitor. Modify Therapy/Monitor Closely. Excessive dosages of Venofer may lead to accumulation of iron in storage sites potentially leading to hemosiderosis. Each mL contains 20 mg of elemental iron. Most adults require a cumulative dose of elemental iron of at least 1 g. Iron replenishment is usually doneintravenously, via iron-dextran, iron sucrose or iron carboxymaltose. This document does not contain all possible drug interactions. Philadelphia, PA: Lippincott Williams & Wilkins;2013;303-307. Applies only to oral form of both agents. 2.1 Dosage - Total dose infusion The dose calculation for CosmoFer is based on patients body weight according to the table below and is diluted in 500mLs of normal saline. Intermediate calculations: -Blood volume (dL) = [65 (mL/kg) x body weight (kg)] / 100 (mL/dL) -Hgb deficit (g/dL) = 14.0 - patient hgb conc. During all INFeD administrations, observe for signs or symptoms of anaphylactic-type reactions. Ferric gluconate: 12.5 mg/mL. Minor/Significance Unknown. May increase risk of hypotension. Brand name: Venofer Drug class: Iron Preparations Chemical name: iron saccharate CAS number: 8047-67-4 Medically reviewed by Drugs.com on Oct 25, 2022. Am J Hosp Pharm. informational and educational purposes only. Most reactions associated with intravenous iron preparations occur within 30 minutes of the completion of the infusion. WARNING: RISK FOR SERIOUS HYPERSENSITIVITY/ANAPHYLAXIS REACTIONS Fatal and serious hypersensitivity reactions including anaphylaxis have occurred in patients receiving Feraheme. Applies only to oral form of both agents. Step 2: Calculation and administration of the maximum individual iron dose(s): . Creating an account is free and takes less than 1 minute. Hemoglobin can be input in g/dL, g/L or mmol/L and refers to the amount of hemoglobin in the red blood cells. Applies only to oral form of both agents. There is limited experience with administration of an infusion of 500 mg of Venofer, diluted in a maximum of 250 mL of 0.9% NaCl, over a period of 3.5 to 4 hours on Day 1 and Day 14 [see How Supplied/Storage and Handling (16.2). Deferoxamine chelates iron. Use Caution/Monitor. Med J Aust. Minor/Significance Unknown. Minor (2)calcium acetate decreases levels of iron sucrose by inhibition of GI absorption. ONE DOSE. iron sucrose decreases levels of liothyronine by inhibition of GI absorption. DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. Deferasirox chelates iron. Although anaphylactic reactions known to occur following INFeD administration are usually evident within a few minutes, or sooner, it is recommended that a period of an hour or longer elapse before the remainder of the initial therapeutic dose is given. official version of the modified score here. Minor/Significance Unknown.iron sucrose increases levels of calcium citrate by enhancing GI absorption. Minor/Significance Unknown. The prevention and treatment of iron deficiency is a major public health goal, especially in women, children, and individuals in low-income countries. Iron supplements, whether administered orally, intramuscular or intravenous, are used to replenish body stores and correct anemia. Separate by 2 hr. Crown Rump Length and Nuchal Translucency. Maximum recommended single dose: 300 mg (See Prescriber's Orders). feasible, Maximum total cumulative iron sucrose dose administered in 14 days is 1000 mg elemental iron. Deferiprone may bind polyvalent cations (eg, iron, aluminum, and zinc), separate administration by at least 4 hr between deferiprone and other medications (eg, antacids), or supplements containing these polyvalent cations. Use Caution/Monitor. Avoid or Use Alternate Drug. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Use Caution/Monitor. Applies only to oral form of both agents. Avoid or Use Alternate Drug. 4. Last updated on Jun 1, 2022. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. Modify Therapy/Monitor Closely. Administer while the patient is in a reclined or semi-reclined position. Indications: Ferrlecit is an iron replacement product for treatment of iron deficiency anemia in adult patients and in pediatric patients age 6 years and older with chronic kidney disease receiving hemodialysis who are receiving supplemental epoetin therapy. For males: LBW = 50 kg + 2.3 kg for each inch of patients height over 5 feet For females: LBW = 45.5 kg + 2.3 kg for each inch of patients height over 5 feet. Fulminant symptoms may include general paleness, confusion or episodes of passing out. Applies only to oral form of both agents. Applies only to oral form of both agents. Dosing: (a) Divide calculated total cumulate dose . Accessed: 4/12/2011. Avoid or Use Alternate Drug. iron sucrose will decrease the level or effect of baloxavir marboxil by cation binding in GI tract. Here are the steps to follow for using this drug dosage calculator: First, enter the value of your Weight and choose the unit of measurement from the drop-down menu. The dosage of Venofer is expressed in mg of elemental iron. Minor/Significance Unknown. IDA symptoms vary, may not be specific and include tiredness, weakness, shortness of breath. Initial symptoms may include hypotension, syncope, unresponsiveness, cardiac/cardiorespiratory arrest. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Interaction only with oral iron administration. Ensure the Intravenous Iron Checklist (see trust guideline) has been completed. Consult your doctor for more details.Remember that it is best to get your vitamins and minerals from food whenever possible. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at a concentration of 1 to 2 mg/mL and administered over 5 to 60 minutes. Use Caution/Monitor. It varies from increases in dietary intake of iron (usually for prophylaxis purposes) to oral, intramuscular or intravenous therapy. rabeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Either increases effects of the other by pharmacodynamic synergism. Administer on 5 different occasions over a 14 day period. Applies only to oral form of both agents. Avoid or Use Alternate Drug. Use Caution/Monitor. For patients receiving hemodialysis, administer Feraheme once the blood pressure is stable and the patient has completed at least one hour of hemodialysis. Keep all medical and lab appointments. FERAHEME Dosing & Administration - Feraheme FERAHEME has flexible dosing for your patients FERAHEME flexible scheduling gives your patients the freedom to receive the iron they need as early as 3 days apart 1 FLEXIBLE DILUTION OPTIONS 1 Dilute full contents of vial (17 mL) in 50 mL to 200 mL of: 0.9% NaCl, or 5% dextrose STORAGE 1 Modify Therapy/Monitor Closely. Use Caution/Monitor. Inspect parenteral drug products visually for the absence of particulate matter and discoloration prior to administration. IDA symptoms are often nonspecific and include tiredness, weakness, shortness of breath. Anaphylaxis may occur with IV iron and resuscitation facilities should be available.11 It would appear that iron polymaltose may have a higher incidence of severe systemic reactions than iron sucrose and ferric carboxymaltose. Human studies not conducted. 10th ed. -Hgb deficit (grams) = Hgb deficit (g/dL) x blood volume (dL) -Iron deficit (mg) = Hgb deficit (grams) x 3.3 (mg Fe/g Hgb) [Note: 3.3 x 0.65 = 2.145] -Volume of parenteral iron product req'd (mL) = [Iron deficit (mg)] / C(mg/mL) Final calculations: -Hgb iron deficit (mg) = weight (kg) x (14 - Hgb) x (2.145) -Volume of product required (mL) = [weight (kg)x (14 - Hgb) x (2.145)] / C Where C= concentration of elemental iron (mg/ml) in the product being used: Iron dextran: 50 mg/mL. The usual total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Iron stores 500 mg for body weight greater than or equal to 35 kg (77 lbs) and 15 mg/kg for body weight less than 35 kg. In most cases, adult patients require a cumulative dose of elemental iron of at least 1 g. Most commonly, iron replenishment therapy is done intravenously: As total dose (iron-dextran or iron carboxymaltose); Iron deficiency is common during childhood growth, prolonged periods of sickness, in convalescence or during pregnancy. Injection: 50 mg/2.5 mL, 100 mg/5 mL, or 200 mg/10 mL (20 mg/mL) in single-dose vials. Administer Injectafer intravenously, either as an undiluted slow intravenous push or by infusion. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. Where C is the concentration of the iron product: Please note that the calculations above are for information purposes only and the individual dose needs to be established by taking into account the current package insert for the elemental iron product used. Suggested regime: Prescribing instructions Prescribing a single/first dose: Dose administration to an elderly patient should be cautious, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy. Monitor for signs and symptoms of hypotension following each administration of Venofer. prescription products. Feraheme does not contain antimicrobial preservatives. Minor/Significance Unknown. To provide clinicians with evidence-based guidance for iron therapy dosing in patients with iron deficiency anemia (IDA), we conducted a study examining the benefits of a higher cumulative dose of intravenous (IV) iron than what is typically administered. Use Caution/Monitor. Option 2: 200 mg in NS 100 mL administered over 20-30 minutes; may repeat every other day to Venofer is given as an infusion into a vein. HOW TO USE: This medication is given by injection into a vein as directed by your doctor. There is limited experience with administration of an infusion of 500 mg of Venofer, diluted in a maximum of 250 mL of 0.9% NaCl, over a period of 3.5 to 4 hours on Day 1 and Day 14. Coadministration of ciprofloxacin with multivalent cation-containing products may reduce the bioavailability of ciprofloxacin by 90%. Use Caution/Monitor. (2010) Diagnosis and management of iron deficiency anaemia: a clinical update. For males: LBW = 50 kg + 2.3 kg for each inch of patients height over 5 feet For females: LBW = 45.5 kg + 2.3 kg for each inch of patients height over 5 feet Administration: I. Intravenous therapy is preferred for urgent intervention and when oral iron cannot be absorbed or the patient suffers from chronic renal impairment. Use INFeD only in patients in whom clinical and laboratory investigations have established an iron deficient state not amenable to oral iron therapy. Do Not Copy, Distribute or otherwise Disseminate without express permission. Alldredge BK, Corelli RL, Ernst ME, Guglielmo BJ, eds. Serious hypersensitivity reactions, including anaphylactic-type reactions, some of which have been life-threatening and fatal, have been reported in patients receiving Venofer. Only administer Feraheme as an intravenous infusion over at least 15 minutes and only when personnel and therapies are immediately available for the treatment of anaphylaxis and other hypersensitivity reactions. 2010;18(3). Your doctor will do laboratory tests to monitor your response. Dilute Venofer in a maximum of 250 mL of 0.9% NaCl [see How Supplied/Storage and Handling (16.2).] 1 Dosing for patients who weigh less than 50 kg For liquid medications, also enter the value of the Medicine Concentration and choose . IV iron sucrose (Venofer) given as divided dosages, and low molecular weight iron dextran (CosmoFer) this can be given as divided dose or as a total dose infusion . Situation Analysis Market Size MAT Sales Cr LC MAT Share % MAT Gr % Total Pharma Market 9388.69 100 13.5 Iron Sucrose 11.18 93.81 37.65 Brand Company Saline MAT . Congenital Pulmonary Airway Malformation Volume Ratio (CVR) Calculator -. It is unlikely . The recipient will receive more details and instructions to access this offer. All Rights Reserved. Use Caution/Monitor. Reference www.medicines.org.uk Background Get in touch with MDApp by using the following contact details: 2017 - 2023 MDApp. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Avoid or Use Alternate Drug. If we don't have the calculator you need then tell us the details and we'll make it for you. Avoid or Use Alternate Drug. Bhowmik D, Modi G, Ray D, Gupta S, Agarwal SK, Tiwari SC, Dash SC. OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Test Dose: Not required. This website also contains material copyrighted by 3rd parties. The dose of Ferinject is based on calculation of ideal body weight and calculation of iron deficit using the Ganzoni formula. *Administer early during the dialysis session. Iron metabolism needs to be balanced and bleeding, the major cause of iron deficiency (for instance in menstruation in females and chronic occult gastrointestinal bleeding) needs to be addressed. Applies only to oral form of both agents. Applies only to oral form of both agents. Applies only to oral form of both agents. Applies only to oral form of both agents. Avoid or Use Alternate Drug. 1988 May;111(5):566-70. Intravenous iron-dextran: therapeutic and experimental possibilities, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Diagnosis and management of iron deficiency anaemia: a clinical update. Minor/Significance Unknown. Avoid or Use Alternate Drug. Contraindicated. Pediatric Patients: The most common adverse reactions (2%) are headache, respiratory tract viral infection, peritonitis, vomiting, pyrexia, dizziness, cough, nausea, arteriovenous fistula thrombosis, hypotension and hypertension. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Monitor Closely (1)trientine, iron sucrose. Use Caution/Monitor. There are three fields in the parenteral iron replacement for iron deficiency anemia calculator: Weight can be input in either lbs or kilograms and the required transformations are performed by the calculator. Applies only to oral form of both agents. Dosage: For patients weighing 50 kg (110 lb) or more: Give Injectafer in two doses separated by at least 7 days. sodium sulfate/?magnesium sulfate/potassium chloride decreases levels of iron sucrose by inhibition of GI absorption. Give each dose as 750mg for a total cumulative dose not to exceed1500mg of ironper course. Each mL contains 20 mg of elemental iron. There are four fields that need to be completed: Weight body weight is used to establish iron deficit and is also taken into account when estimating the iron stores. Monitor Closely (1)sodium sulfate/?magnesium sulfate/potassium chloride decreases levels of iron sucrose by inhibition of GI absorption. Oral iron therapy is the first method while IV therapy comes in place when there are contraindications or the body doesnt respond to the oral one. Serious - Use Alternative (1)iron sucrose decreases levels of ofloxacin by inhibition of GI absorption. Max Dose. Both the 200- and 300-mg doses of IV iron sucrose administered over 2 hours appear to be safe. iron sucrose decreases levels of oxytetracycline by inhibition of GI absorption. iron sucrose decreases levels of ciprofloxacin by inhibition of GI absorption. Parenteral iron dextran therapy. Feraheme, when added to intravenous infusion bags containing either 0.9% Sodium Chloride Injection, USP (normal saline), or 5% Dextrose Injection, USP, at concentrations of 2-8 mg elemental iron per mL, should be used immediately but may be stored at controlled room temperature (25C 2C) for up to 4 hours or refrigerated (2-8 C) for up to 48 hours. Applies only to oral form of both agents. Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. Minor/Significance Unknown. Modify Therapy/Monitor Closely. Applies only to oral form of both agents. Individual plans may vary Separate by at least 4 hours. Sodium ferric gluconate complex injection [ Ferrlecit ] [package insert] - Elemental iron: 12.5 mg/mL (5 mL). Accessed: 4/12/2011. No data are available regarding overdosage of Venofer in humans. Each mL contains 20 mg of elemental iron. Applies only to oral form of both agents. Injection site discoloration has been reported following extravasation. Administer a test INFeD dose prior to the first therapeutic dose. There is no resource limitation, as if the tool was hosted on your site, so all your users can make use of it 24/7; The necessary tool updates will take place in real time with no effort on your end; A single click install to embed it into your pages, whenever you need to use it. IDA diagnosis is based on full blood examination and on the serum ferritin level. Multiple placebo-controlled, randomized clinical trials have been conducted with IV iron in patients with New York Heart Association class II-III heart failure with an ejection fraction 45% who met criteria . FERAHEME was non-inferior to Venofer (iron sucrose) in mean Hgb rise from baseline 2,5. pantoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. For adult CKD patients on ESA therapy who are not receiving iron supplementation, the guideline suggests a trial of IV iron (or in NDD-CKD patients, alternatively, a 1- to 3-month trial of oral iron therapy) if: CKD=chronic kidney disease ESA=erythropoietin-stimulating agent Hb=hemoglobin IV=intravenous RBC=red blood cell WBC=white blood cell. ------------------------------------------------------------------------- Ferric Carboxymaltose [ Injectafer ] Elemental iron: Injectafer contains 50 mg of elemental iron - 750 mg/15 mL [package insert] Indications: Injectafer is indicated for the treatment of iron deficiency anemia in adult patients: who have intolerance to oral iron or have had unsatisfactory response to oral iron; who have non-dialysis dependent chronic kidney disease. Use Caution/Monitor. Applies only to oral form of both agents. Use Caution/Monitor. Applies only to oral form of both agents. If hypersensitivity reactions or signs of intolerance occur during administration, stop Venofer immediately. Reactions have occurred following the first dose or subsequent doses of Venofer. Avoid or Use Alternate Drug. Use Caution/Monitor. Intravenous (IV) iron products (use in adults) Dosing information in this table is for adults and includes some dosing recommendations not listed in the approved product information. Applies only to oral form of both agents. Applies only to oral form of both agents. A healthcare provider will give you this injection. The dosing for iron replacement treatment in pediatric patients with HDD-CKD has not been established. LBW = Lean body weight in kg. Minor/Significance Unknown. Use Caution/Monitor. Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. This drug is available at a higher level co-pay. Iron supplements, regardless of their way of administration, are used to replete body stores and to correct anemia. Then enter the value of the Dosage and choose the unit of measurement from the drop-down menu. Applies only to oral form of both agents. Most studies have used IV iron sucrose (maximum dose of 200 mg per setting) or ferric carboxymaltose (maximum dose of 1000 mg per week). (3) Known hypersensitivity to Venofer. Hemoglobin there are two fields for hemoglobin input, one for the target and another for actual value. Pregnancy: Risk Summary-Clinical Considerations. Minor/Significance Unknown. didanosine will decrease the level or effect of iron sucrose by increasing gastric pH. The total amount of INFeD in mL required to treat the anemia and replenish iron stores may be approximated as follows: Adults and Children over 15 kg (33 lbs): See Dosage Table. Found in multiple references. Applies to didanosine chewable tablets and powder for oral solution; administer 2 hr before or several hours after didanosine oral solution or chewable tablet administration. . and formulary information changes. Nutrition. Dr. Ganzonis primary research is focused on iron deficiency and plasma iron transport. Although the original formula requires the weight in kilograms, values input in lbs are transformed. 1995 Mar-Apr;11(2):163-8. Dose. concentration of elemental iron (mg/ml) in the product being used: This calculator will help pinpoint potential causes of anemia based on an automated flowchart approach. Monitor Closely (1)sodium sulfate/potassium sulfate/magnesium sulfate decreases levels of iron sucrose by inhibition of GI absorption. Separate dosing of tetracyclines from these products. By entering this website, you acknowledge that you are a licensed healthcare professional practicing in the United States. famotidine will decrease the level or effect of iron sucrose by increasing gastric pH. Baloxavir may bind to polyvalent cations resulting in decreased absorption. The following table present normal hemoglobin ranges: There is another equation for iron deficit that can be used to calculate replenishment needs, that of Ganzoni, which takes into account iron stores as well and that can be found in the iron deficit calculator. Results: Twelve children (6 females) aged 1.2-14 years (median age 8.9 years) received at least one dose of . Applies only to oral form of both agents. iron sucrose increases levels of calcium chloride by enhancing GI absorption. Equations : Total body iron deficit (mg) = body weight (kg) x (target Hb - actual Hb in g/dL) x 2.4 + iron depot (mg)** [1, 2] Iron depot: 15 mg/kg for body weight less than 35 kg 500 mg for those with a body weight greater than or equal to 35 kg Ideal Body Weight (kg) =45.5 +2.3 * (height inches - 60 inches) [3] UpToDate. Copyright 2021 GlobalRPH - Web Development by, Calculation of the Total Iron Deficit Alternative equation. Allow at least 30 minutes between administration of Feraheme and administration of other medications that could potentially cause serious hypersensitivity reactions and/or hypotension, such as chemotherapeutic agents or monoclonal antibodies. iron sucrose decreases levels of methyldopa by inhibition of GI absorption. Dosing Administration & Considerations . 1996 Aug;11(4):139-46. Use Caution/Monitor. Normal haemoglobin values are gender specific: for males from 13.8 to 18.0 g/dL (138 to 180 g/L, or 8.56 to 11.17mmol/L) and females from 12.1 to 15.1 g/dL (121 to 151 g/L, or 7.51 to 9.37mmol/L). VenAccess is a trademark of Vifor (International) Inc. Switzerland. Administer Feraheme as an intravenous infusion in 50-200 mL 0.9% Sodium Chloride Injection, USP or 5% Dextrose Injection, USP over at least 15 minutes. 1. Avoid or Use Alternate Drug. VENOFER at IV doses up to 15 mg iron/kg/dose [about 10 times the maximum recommended human dose for a 70 kg person] given three times a week was found to have no effect on fertility . Administer Venofer early during the dialysis session (generally within the first hour). This site complies with the HONcode standard for trust- worthy health information: verify here. Deferasirox chelates iron. When to Use Weight lbs Target hemoglobin g/dL Actual hemoglobin g/dL Iron stores Use 500 mg for adults and children 35 kg; use 15 mg/kg if <35 kg mg Result: Please fill out required fields.
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